Extended Data Fig. 6: Single-cell transcriptomics resolves the memory associated genes in astrocytes.
From: Spatial transcriptomics reveal neuron–astrocyte synergy in long-term memory
a) Ntsr2 expression is enriched in astrocytes among all cells in BLA. b) Cluster of astrocytes from BLA. c) Expression level of astrocyte pan markers (Slc1a2, Aldoc, and Slc1a3). d) Heatmap of top marker genes of BLA astrocyte clusters. e) Cellular trajectory estimation of BLA astrocytes, based on gene expression. f) Fos expression of BLA astrocytes. g) Fos expression of astrocyte clusters h) Astrocyte composition separated by training conditions. i) Distinct markers for each astrocyte cluster from BLA. j) Syne1 expression data, retrieved from Allen Atlas. k) RNAscope in situ stanning of Syne1 and tdTomato in BLA of NF and FR conditions. l-p) DEGs of FR vs. NF in Astro_1 – 5, unadjusted P value by Mann Whitney Wilcoxon test. All scRNAseq data, except i and j.
