Extended Data Fig. 10: The cleft in OSCA channels.
From: Mechanical activation opens a lipid-lined pore in OSCA ion channels
Characterization of the cleft in OSCA channels was performed on both published structures and the structures obtained in this study. Distances were measured between the residues labeled in the bottom structures. Areas were measured within the colored parallelogram in each model. Cleft angles were determined by measuring the angle between the TM3 helices on each monomer, using Chimera.
