Extended Data Fig. 10: Brig1 homologues.
From: DNA glycosylases provide antiviral defence in prokaryotes
a, Gene neighbourhoods of Brig1 homologues found in putative anti-phage defence islands. Brig1 homologues and other DNA glycosylases are shown in magenta, Pgl/BREX genes in brown, and other putative defence genes in grey. b, Gene neighbourhood of the Brig1 homologue from Nocardioides zhouii showing ADP-ribosyl glycohydrolase, transposase and putative anti-phage defence genes in orange, yellow and grey, respectively. c, Same as b but for the Brig1 homologue from Nocardioides anomalus. d, AlphaFold2 structure of the Brig1 homologue from N. zhouii, coloured by position (N-terminal, blue; to C-terminal, red). e, Same as d but coloured by pLDDT (a per-residue model confidence score). Red to blue spectrum represents high to low confidence of secondary structure prediction. f, Same as d but showing the AlphaFold2 structure of the Brig1 homologue from N. anomalus. g, Same as e but showing the AlphaFold2 structure of the Brig1 homologue from N. anomalus.
