Extended Data Fig. 8: Association of mutational signatures with incidence of renal cancer. | Nature

Extended Data Fig. 8: Association of mutational signatures with incidence of renal cancer.

From: Geographic variation of mutagenic exposures in kidney cancer genomes

Extended Data Fig. 8

Number of mutations attributed to signatures (a) SBS40a, (b) ID5 and (c) ID8 against age-standardized incidence rate (ASR) of kidney cancer in each of the eleven countries represented in the cohort. Data are presented as mean values +/− SEM (n = 961 biologically independent samples examined over 1 independent experiment). The p-values shown are for the ASR variable in linear regressions across all cases, adjusted for sex and age of diagnosis.

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