Extended Data Fig. 8: Molecular basis of spatial prioritization at the gene level.
From: Single-cell and spatial atlases of spinal cord injury in the Tabulae Paralytica
a-c, Volcano plots showing correlations between the AUCs assigned by Magellan at each spatial barcode and transcriptome-wide gene expression across the same spatial barcodes (a, 7 days versus uninjured; b, 2 months versus uninjured; c, 7 days versus 2 months). Inset pie charts show the proportions of all tested genes that are significantly correlated with the spatial prioritizations. d, Heatmap showing Pearson correlations between spatial prioritizations and gene expression for each pairwise comparison of experimental conditions, for the top 40 most recurrently correlated genes across all comparisons. e, Heatmap showing Pearson correlations between spatial prioritizations and gene expression for each pairwise comparison of experimental conditions, for the top 40 most variably correlated genes across all comparisons. f, Visualization of selected genes prioritized by their correlation to spatial prioritizations on the two-dimensional coordinate system of the injured spinal cord.
