Extended Data Fig. 2: Glial subpopulation diversity.
From: Cellular communities reveal trajectories of brain ageing and Alzheimer’s disease
(a,d,g) Subpopulation proportions across participants for (a) microglia, (d) astrocytes and (g) oligodendroglia cells. Dots: 465 individual participants. Box: 1st and 3rd quartiles; line: median, whiskers extend to the highest and lowest values within 1.5 times the distance between the quartiles. (b,e,h) QC measures. Distributions of number of UMIs and number of Genes detected for each subpopulation of (b) microglia, (e) astrocytes and (h) oligodendroglia. (c,f,i) Selected markers and top differentially expressed genes between subpopulations. Gene expression (columns) across subpopulations (rows) of (c) microglia, (f) astrocytes and (i) oligodendroglia. Dot colour: mean expression in expressing cells. Dot size: percent of cells expressing the gene.
