Extended Data Fig. 7: Comparisons of expansion clonal fractions across cell types and individuals.

a, Clonal fractions inferred from the phylogeny compared to targeted sequencing of monocytes. Plot shows only clones that are at least 5% clonal fraction in either donor or recipient. The x-axis shows clonal fractions inferred from the proportion of colonies from that individual coming from that clone, with circles denoting the point estimate and error bars giving the 95% confidence interval (exact binomial test). The y-axis shows clonal fractions inferred from the deep targeted sequencing of monocyte fractions. Confidence intervals for the targeted sequencing data are generally narrow and therefore not shown. b,c, Bar plots showing the log₂ fold change of expanded clone sizes within monocytes (b) or B-cells (c) comparing recipients to their donors. Bars are coloured red if the clone is larger in the recipient, or blue if larger in the donor.