Extended Data Fig. 11: Relative clonal fraction of driver events in different mature cell compartments.

a, Dot plot showing the log₂ fold change of putative driver event VAFs in recipients compared to donors in monocytes (left panel), B-cells (middle panel) and T-cells (right panel). Points are coloured by whether fractions are lower (orange) or higher (green) in recipients, or show no significant difference (blue). Circles show the point estimate and error bars show the 95% confidence interval of the log₂ fold change. Variants are grouped by the affected gene or chromosome. Where mutations occur on the background of another driver mutation, genes are shown in the format GENE1/ GENE2, indicating that all cells in the clone have driver mutations in both genes. Where the mutant clone contains a major subclone with an additional driver mutation, these are shown in the format GENE1 (GENE2), indicating that some, but not all cells in the clone have driver mutations in both genes. LOY, loss of the Y chromosome.