Fig. 2: The numbers of long-term engrafting haematopoietic stem cells.

a, The posterior distributions for the number of long-term engrafting HS cells for each HCT, as estimated by approximate Bayesian computation (Methods). b, The relationship between the number of engrafting HS cells and the infused CD34⁺ cell dose per kg of recipient body weight. The points show the median posterior value, and error bars show the 95% posterior intervals, calculated from the 1% of n = 100,000 simulations of which the summary statistics best matched the observed data. CD34⁺ cell dose was not available for pairs 3, 6, 7 or 8. c, As in b, but illustrating the relationship between the numbers of engrafting HS cells and the age of the donor at the time of HCT. GCSF, granulocyte colony-stimulating factor; PB, peripheral blood.