Extended Data Fig. 2: Combined donor-in-donor and donor-in-recipient phylogenies. | Nature

Extended Data Fig. 2: Combined donor-in-donor and donor-in-recipient phylogenies.

From: Clonal dynamics after allogeneic haematopoietic cell transplantation

Extended Data Fig. 2

Phylogenies have been made ultrametric and scaled to real time (Methods). Grey shaded boxes indicate the approximate time of HCT. Branches with driver mutations are shown (red dashed lines) labelled with the mutant gene. Branches were found in donor HSPCs only (cyan), recipient HSPCs only (pink) or both (black). Heatmaps show additional colony-level information. HCT, haematopoietic cell transplantation; LOY, loss of Y chromosome; CNA, Copy number alteration; Recip, Recipient, Zyg., Zygote.

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