Supplementary Figure 15: Pseudodynamics model fit to the continuous pancreatic beta cell maturation data set.
From: Inferring population dynamics from single-cell RNA-sequencing time series data
(a-f) Kernel density estimator of observed density (shaded) and best model fit (lines) of β-cell population density across cell state by time point for models with state- (s) or state- and time-dependent (st) birth-death rates. (g) Observed number of β-cells in black with one standard deviation around the mean as error bars and population size fits by model with the following number of replicates per time point: n = 3 at t = 0, n = 3 at t = 5.5, n = 3 at t = 10.5, n = 8 at t = 11.5, n = 3 at t = 15.5, n = 5 at t = 46.5. Replicates were separately measured in one unique animal per replicate.
