Supplementary Figure 1: CAR stratification by normal expression and recent usage in the clinic. | Nature Biotechnology

Supplementary Figure 1: CAR stratification by normal expression and recent usage in the clinic.

From: The therapeutic landscape for cells engineered with chimeric antigen receptors

Supplementary Figure 1

(a) The number of trials from 2017–2019 that used a given CAR compare to the percent of tissues with medium-high levels of expression of the CAR target. (b) The percentage of tissue groups with not-detected, low, medium, or high levels of target expression based on maximum expression seen within a cell type for CARs used in multiple recent trials. (c) Tissue group, (d) tissue, and (e) cell types with a given CAR target highly expressed. CARs examined are listed in (b).

Back to article page