Extended Data Fig. 2: Expression of BE3RA across different tissues in mice carrying one or two copy of each allele. | Nature Biotechnology

Extended Data Fig. 2: Expression of BE3RA across different tissues in mice carrying one or two copy of each allele.

From: Generation of precision preclinical cancer models using regulated in vivo base editing

Extended Data Fig. 2

Immunofluorescent detection of Cas9 protein in rtTA3+/- iBE+/- (iBEhem), rtTA3+/+ iBE+/-, rtTA3+/- iBE+/+ and rtTA3+/+iBE+/+ (iBEhom) mice maintained on dox chow for 14 days. Cas9 protein(green), DAPI staining for nuclei (blue) across four tissues analyzed. (n=3 mice per genotype and condition).

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