Extended Data Fig. 3: Benchmarking of robustness to tuning parameters in MaxFuse integration on CITE-seq PBMC with all 228 antibodies from Hao et al.33, evaluated by matching accuracy at two levels.
From: Integration of spatial and single-cell data across modalities with weakly linked features
(A) Matching accuracy (cell type level 1) versus a range of SVD components for different modalities, smoothing weights during initialization and refinement, filtering percentages on pivot and on full matching, number of iterations, final CCA embedding dimensions, meta-cell size, and NN-graph neighborhood size. Line indicates mean value and shadow indicates 95% CI on both sides. (B) Matching accuracy (cell type level 2) versus a range of SVD components for different modalities, smoothing weights during initialization and refinement, filtering percentages on pivot and on full matching, number of iterations, final CCA embedding dimensions, meta-cell size, and NN-graph neighborhood size. Line indicates mean value and shadow indicates 95% CI on both sides.
