Extended Data Fig. 1: MMR-evading edits support more efficient prime editing. | Nature Biotechnology

Extended Data Fig. 1: MMR-evading edits support more efficient prime editing.

From: Engineered virus-like particles for transient delivery of prime editor ribonucleoprotein complexes in vivo

Extended Data Fig. 1

Installation of nearby mutations improves prime editing efficiencies of v2.3 PE-eVLPs at the HEK3 locus and Dnmt1 locus in HEK293T and N2A cells respectively. Values shown in all graphs represent the average prime editing efficiency of three biological replicates and error bars represent the standard deviation. Data were fitted to four-parameter logistic curves using nonlinear regression.

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