Extended Data Fig. 3: Accompaniment to Fig. 3.
From: Continuous multiplexed phage genome editing using recombitrons

a. Comparison of edited phages measure by amplicon (Illumina) or amplification-free (Oxford Nanopore) sequencing. Open orange circles represent biological replicates of amplicon data and filled orange circle represents the mean. Filled blue circle represents the aggregate nanopore data from three replicates. b. Coverage of the editing site in long-read nanopore sequencing for deletions in which we observe editing. c. Coverage of the editing site in long-read nanopore sequencing for deletions in which we do not observe any edits. Estimated limit of detection for these samples is calculated by dividing 100 by the coverage of the site. d. Examples of nanopore reads for different deletion conditions. e. Coverage of the editing site in long-read nanopore sequencing for large insertions, for which we do not observe any edits. Estimated limit of detection for these samples is calculated by dividing 100 by the coverage of the site.