Escherichia coli engineered to display cytokines destroy hard-to-treat tumors by boosting the activity of local native and adoptive immune effector cells.
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L.Z. is the founder of EverImmune Cie and its scientific advisory board president, has a research contract with Pileje, and was on the board of directors of Transgene for 9 years.
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Fidelle, M., Zitvogel, L. Bacteria displaying cytokines heat up the tumor microenvironment. Nat Biotechnol (2024). https://doi.org/10.1038/s41587-024-02429-3
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DOI: https://doi.org/10.1038/s41587-024-02429-3
