Fig. 6: Cell-type-specificity network across the 59 quantitative traits and 30 diseases in the 220 cell-type-specific annotations. | Nature Genetics

Fig. 6: Cell-type-specificity network across the 59 quantitative traits and 30 diseases in the 220 cell-type-specific annotations.

From: Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases

Fig. 6

Significant heritability enrichments connect cell types to phenotypes. Each circle represents a trait, and each square represents a cell type. Arrows denote significant heritability enrichments for the indicated traits. The significance of heritability enrichment was estimated via stratified LD score regression. FDR was calculated via the Benjamini–Hochberg method. Thicker edges/arrows correspond to more significant FDRs. The dashed line separates unconnected plots. We used highly significant enrichments (FDR < 0.01). Definitions for abbreviations are as in Fig. 5 and Tables 1 and 2.

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