Supplementary Figure 6: Additional mutation characteristics of individual SMGs. | Nature Genetics

Supplementary Figure 6: Additional mutation characteristics of individual SMGs.

From: The long tail of oncogenic drivers in prostate cancer

Supplementary Figure 6

(a) CUL3 mutations observed in our cohort. (b) Mutations observed in PIK3R2. Hotspot mutations observed in PIK3R2 are paralogous to the oncogenic D560 mutation in PIK3R1. (c) Mutation distribution of CDK12 variants, showing that the majority of mutations are truncating and that missense variants cluster in the kinase ___domain.

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