Supplementary Figure 3: Structural conformation of the active and inactive β-globin locus. | Nature Genetics

Supplementary Figure 3: Structural conformation of the active and inactive β-globin locus.

From: Single-allele chromatin interactions identify regulatory hubs in dynamic compartmentalized domains

Supplementary Figure 3

Contact matrices (4-kb resolution) of the β-globin locus derived from Capture-C experiments with viewpoints closely spaced across the ___domain in erythroid (top) and ES (bottom) cells. Matrices represent the mean number of normalized unique interactions in three replicates. Gene annotation (β-globin genes highlighted in red), erythroid DNase I hypersensitivity (DHS) and CTCF occupancy are shown in the middle. Coordinates (mm9): chr7:110,840,000–111,140,000.

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