Extended Data Fig. 3: m6A is present on the majority of RNA:DNA hybrids in hiPSCs.
From: N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells
m6A is present on the majority of RNA:DNA hybrids in hiPSCs. (a) Heatmaps showing the distribution of density of indicated reads across genomic regions containing peaks (3 kb around peak center) of the three categories: m6A peaks overlapping with S9.6 peaks (m6A/S9.6), m6A peaks that do not overlap with S9.6 DRIP peaks (m6A only) and S9.6 peaks that do not correspond to m6A DIP peaks (S9.6 only). The colour of each line represents the density of reads for a given peak. The width of the heatmaps is normalized by peak length. (b, c) Distribution of the m6A/S9.6-, m6A only- and S9.6 only peaks at the indicated genomic features (b) and relative to transcription start site (TSS) (c) in hiPSCs.
