Extended Data Fig. 6: Heatmap showing patterns of correlated GWAS effect sizes between psychiatric disorders and behavioral-cognitive phenotypes for variants affecting RBP dysregulation. | Nature Genetics

Extended Data Fig. 6: Heatmap showing patterns of correlated GWAS effect sizes between psychiatric disorders and behavioral-cognitive phenotypes for variants affecting RBP dysregulation.

From: Genome-wide landscape of RNA-binding protein target site dysregulation reveals a major impact on psychiatric disorder risk

Extended Data Fig. 6

For each pair of disorder and phenotype (x,y), we extracted the top RBP dysregulation set of variants that influence disorder x and their GWAS effect sizes on both x and y. We then calculated correlation between the GWAS effect sizes on x and the GWAS effect sizes on y, and tested whether this correlation was significantly different from zero. Stars represent statistical significance *** P < 0.001, ** P < 0.01, * P < 0.05.

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