Extended Data Fig. 6: Diversity of eight classical HLA genes in the constructed multi-ancestry MHC reference panel.

Each gene is stratified by six populations (AA, Admixed African; EAS, East Asian; EUR, European; LAT, Latino; SAS, South Asian). The top two most common alleles within each classical gene of each population are plotted across all panels. Alleles that have frequencies greater than 1% are also labelled in the bar plots. a, Class I genes. b, Class II genes.