Extended Data Fig. 5: Distribution of individual PRS absolute standard deviation with respect to heritability under different polygenicity. | Nature Genetics

Extended Data Fig. 5: Distribution of individual PRS absolute standard deviation with respect to heritability under different polygenicity.

From: Large uncertainty in individual polygenic risk score estimation impacts PRS-based risk stratification

Extended Data Fig. 5

Each panel represents simulation with one polygenicity from \(\left\{ {0.001,0.01,0.1,1} \right\}\). The x-axis is five heritability parameters (\(h_g^2 \in \left\{ {0.05,0.1,0.25,0.5,0.8} \right\}\)). The y-axis is scaled standard deviation in PRS estimation of an individual. Each violin plot represents 21,273 testing individuals across 10 simulations (212,730 values).

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