Fig. 1: Overview of the study. | Nature Genetics

Fig. 1: Overview of the study.

From: Brain expression quantitative trait locus and network analyses reveal downstream effects and putative drivers for brain-related diseases

Fig. 1

We downloaded publicly available RNA-seq and genotype data from 14 different datasets consisting of 8,613 RNA-seq measurements from seven main brain regions and 6,518 genotype samples. We created six eQTL meta-analysis datasets and performed cis-, trans- and interaction-eQTL analyses, built a brain-specific gene co-regulation network and prioritized genes using MR, co-localization and the co-regulation network. Image of sagittal cut of brain created with BioRender.com. This figure summarizes values from Supplementary Tables 1, 3, 8, 12 and 25–30.

Back to article page