Extended Data Fig. 9: Repetitive nature of antigens and optimal antigen combination for TCGA.
From: Pan-cancer analysis identifies tumor-specific antigens derived from transposable elements
a, Number of genomic loci HLA-bound TE peptides from another study could originate from using BLAT. b, mTEC and TEC expression of all 2,297 candidates. c, Bar graph of the number of mTEC or TEC samples the candidate is detected in. Only those candidates found in multiple mTEC or TEC samples are shown. d, Bar graph of the number of tumor samples that each candidate is present in for the optimal combination of 20 TS-TEAs that would cover the most TCGA samples (bottom). At the top, a line plot showing the cumulative number of tumor samples covered by that number of candidates.
