Extended Data Fig. 2: Annotation of single cell RNA and ATAC datasets. | Nature Genetics

Extended Data Fig. 2: Annotation of single cell RNA and ATAC datasets.

From: Integrated single-cell chromatin and transcriptomic analyses of human scalp identify gene-regulatory programs and critical cell types for hair and skin diseases

Extended Data Fig. 2

(a) UMAP projections of full scRNA-seq dataset colored by relative expression levels of representative cell compartment marker genes. (b) UMAP projections of full scATAC-seq dataset colored by relative gene activity scores of the same marker genes shown in (A). (c) Marker peaks (Wilcoxon FDR ≤ 0.1 and Log2 fold change ≥ 0.5) for each scATAC cluster. (d) The fraction of each scRNA-seq cluster comprising each sample. The total proportions for each cluster are shown in the rightmost column. (e) The fraction of each scATAC-seq cluster comprising each sample. The total proportions for each cluster are shown in the rightmost column.

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