Table 3 MR-MEGA fine-mapping results for loci with a single SNP within the 95% credible set
From: Multi-ancestry genome-wide association meta-analysis of Parkinson’s disease
Locus | Number of significant SNPs | Nominated variant | CHR:BP:A1:A2 | Nearest gene | Known PD gene ± 1 MB | Functional consequence | CADD | RDB |
|---|---|---|---|---|---|---|---|---|
11 | 6 | 2:135464616:A:G | TMEM163 | TMEM163 | intronic | 6.746 | 4 | |
19 | 926 | 4:951947:C:T | TMEM175 | TMEM175 | exonic | 11.09 | NA | |
23 | 1483 | 4:90626111:A:G | SNCA | SNCA | ncRNA intronic | 8.962 | NA | |
24 | 121 | 4:114369065:T:C | CAMK2D | CAMK2D | intergenic | 1.216 | 3a | |
45 | 1371 | 12:123326598:G:T | HIP1R | HIP1R | intronic | 2.403 | 2b | |
60 | 1 | 19:2341047:C:T | SPPL2B | LSM7 | ncRNA exonic | 1.096 | 5 |
