Extended Data Fig. 5: Overlap of QTL across molecular traits. | Nature Genetics

Extended Data Fig. 5: Overlap of QTL across molecular traits.

From: Epigenetic variation impacts individual differences in the transcriptional response to influenza infection

Extended Data Fig. 5

(A) Left: The number of overlaps for each QTL type for the permuted analysis in the non-infected condition. More than one overlap indicates the QTL is shared with at least one other datatype. Center: The number of overlaps for each QTL type in the flu-infected condition. Right: The number of overlaps for each QTL type for the permuted analysis in the flu-infected condition. (B) The percentage of QTL in one data type that are also QTL for another data type in the flu-condition. The starting QTL (rows) are the QTL that are tested for sharing while the overlapping QTL (columns) are the percentage of each starting QTL that are shared with that datatype. The color of each circle corresponds to the percentage of sharing. (C) QTL sharing patterns for those QTL overlapping 2≥ data types) in the non-infected condition. Y axis the proportion of overlapping QTL (that is, the denominator is the number of QTL that are shared in at least 2 or more data types). (D) QTL sharing patterns for those QTL overlapping 3≥ data types) in the non-infected condition highlighting that caQTL, K4me1 QTL and meQTL are the most commonly shared. The Y axis is the same as described in (C) above.

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