Extended Data Fig. 1: Performance of shet estimates from a model with some features removed.
From: Bayesian estimation of gene constraint from an evolutionary model with gene features
a, Scatterplot of posterior mean shet estimated from a model trained without missense constraint or cross-species conservation features (y axis) against shet estimated from the full model (x axis). b, Precision–recall curves comparing the performance of shet estimated from the full model (blue) and from the model without missense/conservation features (orange) in classifying essential genes. c, Precision–recall curves comparing the performance of shet estimated from the two models in classifying developmental disorder genes.
