Fig. 4: Genomic and epigenomic events surrounding AR.
Top to bottom, genes (with AR in blue), net Hi-C contact frequency (log10) across our samples, TAD structure across our samples where the TADs of all samples are overlayed, average CN variation across our samples from WGS, published prostate cancer ERG and AR chromatin interaction analysis using paired-end tag sequencing (ChIA–PET), 5hmC peaks across our samples from 5hmC-seq, HMRs across our samples from WGBS and published prostate cancer ChIP–seq for H3K27ac. The red dashed lines indicate the border of TAD regions corresponding to common AR locus amplification borders.
