Extended Data Fig. 6: YY1 chromatin binding dynamics during the mitosis-to-G1 transition.
From: YY1-controlled regulatory connectivity and transcription are influenced by the cell cycle
a, Representative plots of the gating strategy for purification of mitosis-to-G1 populations. b, Heatmap showing the Pearson correlation in YY1 occupancy between biological replicates of YY1 ChIP–seq for mitosis-to-G1 stages. c, YY1 ChIP–qPCR in asynchronous (async) cells and synchronized/sorted prometaphase cells. Primers, labeled with the nearest or overlapping gene, include YY1 binding sites that display mitotic retention as well as sites that have no mitotic retention on ChIP–seq (n = 3 biological replicates). d, Prometaphase YY1 ChIP–seq track plotted alongside in silico generated tracks simulating prometaphase background and various levels of interphase contamination. e, Box plot showing YY1 binding at retained peaks genome-wide for different levels of simulated interphase contamination (two-sided Mann–Whitney U test).
