Extended Data Fig. 5: sQTL replication. | Nature Genetics

Extended Data Fig. 5: sQTL replication.

From: Single-cell RNA sequencing of peripheral blood links cell-type-specific regulation of splicing to autoimmune and inflammatory diseases

Extended Data Fig. 5

The results of AIDA cis-sQTLs were replicated in BLUEPRINT (a), DICE (b), ImmuNexUT (c), GTEx whole blood (d), and GTEx lymphoblastoid cell lines (e). The proportions of replicated sQTLs were used to quantify the replication of independent cis-sQTLs in BLUEPRINT (BP), DICE, GTEx and ImmuNexUT for all matched cell types. Replicated sQTLs mean the AIDA independent cis-sQTLs with summary statistics available in BP, DICE, and GTEx and are significant with FDR < 0.05. Each bar plot represents the replicated sQTLs’ proportions in all the cis-sQTLs which have summary statistics in corresponding databases.

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