Fig. 3: Characterization of adipocyte clusters of hSAT and hVAT.

a, UMAP representations of the in-house hSAT and hVAT adipocyte atlases and the combined hSAT and hVAT adipocyte atlas of Emont et al.9. Each UMAP is colored by the adipocyte subtypes defined herein (for hSAT and hVAT) or by Emont et al. (right). b–g, UMAP representations of hSAT, hVAT and Emont et al. adipocyte atlases: lipid metabolism (b); angiogenesis (c); innate immune (d); adaptive immune (e); ECM (f); and mito-ribosomal (g). Each cluster is colored by its mean normalized enrichment scores (NES) for GO annotations related to the process specified in the panel (see color legend at bottom right). Adipocyte subtypes were enriched for distinct processes, suggesting that they have different functionalities.