Extended Data Fig. 1: Parallel glycolysis bolsters growth acceleration upon carbon and nitrogen upshifts.
From: A parallel glycolysis provides a selective advantage through rapid growth acceleration
a, WT and ∆edd strains had been cultured on acetate as the sole carbon source and, at t = 0 min, were spiked with glucose. Growth rates were monitored until a steady growth rate of ~0.7 hr–1 was achieved 80 minutes after upshift. b, WT and ∆edd strains were cultured on arginine as the sole nitrogen source before ammonia was spiked in at t = 0 min. Growth rates were monitored until a stable growth rate of ~0.75 hr–1 was achieved. c, The growth rates of WT and ∆edd were measured in glucose minimal media with and without high acetate and compared to the stable growth rates of E. coli cultures following carbon upshift from acetate to glucose spiked in. Error bars represent the s.e.m. (n = 3 biological replicates).
