Extended Data Fig. 2: The ED pathway improves growth acceleration upon carbon upshift from non-glycolytic to glycolytic substrates.
From: A parallel glycolysis provides a selective advantage through rapid growth acceleration
a, WT and ∆edd cultures had been grown on succinate or glycerol as the sole carbon source and, at t = 0 min, were spiked with glucose. Growth rates and growth acceleration, which is the time derivative of growth rate, were quantified. b, Cells had been grown on a PTS sugar mannose as the sole carbon source and, at t = 0 min, were spiked with glucose. Growth rates as well as growth acceleration over two time periods were quantified. c, Cells were subjected to carbon upshift from acetate to succinate, both gluconeogenic substrates at t = 0 min. Growth rates and growth acceleration were quantified. Error bars represent the s.e.m. (n = 3 biological replicates). P values are obtained by two-tailed t-tests.
