Extended Data Fig. 2: The selectivity of Ebio1 on several ion channels.
From: A small-molecule activation mechanism that directly opens the KCNQ2 channel
a, Summary of the effects of Ebio1 on TREK1, BK, hERG, CaV2.1, and NaV1.1 channels. Statistical analysis: one-way ANOVA with Dunnett’s test. b-f, The representative current traces of TREK1 (b), BK (c), hERG (d), CaV2.1 (e), and NaV1.1 (f) channels in the absence and the presence 10 μM Ebio1 are shown. n = 3, 3, 3, 2, 2 and 2 biological replicates (a). Data are presented as the means ± s.e.m.
