Supplementary Figure 4: Generation of Sros1 knockout mice via CRISPR−Cas9 approach. | Nature Immunology

Supplementary Figure 4: Generation of Sros1 knockout mice via CRISPR−Cas9 approach.

From: Inducible degradation of lncRNA Sros1 promotes IFN-γ-mediated activation of innate immune responses by stabilizing Stat1 mRNA

Supplementary Figure 4

a, Schematic illustration of the deleted region in Sros1−/− mice. b, RT−PCR analysis of genomic region from Sros1−/− and the littermates. c, qRT−PCR analysis of Sros1 in peritoneal lavages. Data are representative of three independent experiments (b) or three independent experiments with n=3 biological replicates (c; shown as mean and s.e.m.). Individual data points represent individual biological replicates. *P<0.05, **P<0.01, ***P<0.001, two−tailed unpaired Student’s t−test.

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