Extended Data Fig. 6: Surface_markers_and_WNT-associated_gene_loci_comparing_CD56^dim_and_CD56^hiNK_cells.

a,b, Detection of CD16 (n = 4), KIR2DL1 (n = 7), KIR2DL2/3 (n = 8), KIR3DL1 (n = 8) and CD57 (n = 8) in CD56^dim and CD56^hiNK cells from PBMCs, mean ± s.e.m.; two tailed paired t-test, *p < 0.001. c, Sorted, CFSE labelled CD94⁺CD56^hiNK cells were cultured in IL-12 (10 ng/ml) and IL-15 (10 ng/ml) for 5 days. Proliferation, CXCR6, and CD57 were detected as indicated. CD56^dim and CD56^hi NK cells from fresh, unstimulated PBMCs were used as control. d, H3K4me3 CUT&RUN and ATAC-Seq signals for gene loci of WNT signaling components and WNT target genes in the indicated NK cell subsets. AXIN1, in contrast, is a WNT inhibitory gene. Data are from HIV-1^– blood donors.

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