Extended Data Fig. 4: Epitope characterization of top 40 RBD-specific antibodies. | Nature Immunology

Extended Data Fig. 4: Epitope characterization of top 40 RBD-specific antibodies.

From: Infection with wild-type SARS-CoV-2 elicits broadly neutralizing and protective antibodies against omicron subvariants

Extended Data Fig. 4

Epitope specificity was determined by competition with ACE2, typical class 1 (P2C-1F11 and REGN10933), class 2 (P2B-2F6), and class 3 (REGN10987 and S309) antibodies measured by surface plasmon resonance (SPR). For clarity, the five antibodies had their crystal or cryo-EM structures resolved in complex with RBD or S trimer are highlighted in either red (class 1) or back (other classes) background. G1 to G5: group 1 to group 5.

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