Extended Data Fig. 6: Haematopoietic progenitor abnormalities in APLAID indicated by a colony assays.
Type and numbers of colonies from 25,000 unfractionated BM cells and 50,000 splenocytes cultured in G-SCF (103 U/mL), GM-CSF (103 U/mL), SIE [SCF, (100 ng/mL), IL-3 (10 ng/mL), EPO (2 U/mL)] were scored after 7 days. Animals were 4 weeks old at time of irradiation and reconstitution. Error bars represent mean ± SEM. Statistical significance for total colonies was determined by an unpaired two-sided Student’s t-test between groups (n = 3 mice per genotype).
