Extended Data Fig. 2: Anti-S-RBD IgG levels and neutralizing antibody titers are correlated and respond differently to various vaccine combinations. | Nature Immunology

Extended Data Fig. 2: Anti-S-RBD IgG levels and neutralizing antibody titers are correlated and respond differently to various vaccine combinations.

From: High-dimensional analysis of 16 SARS-CoV-2 vaccine combinations reveals lymphocyte signatures correlating with immunogenicity

Extended Data Fig. 2

Fold change in a, anti-S-RBD IgG levels (n = 420) and b, neutralizing antibody titers (n = 421) at T3 compared to the mean per group at T1. Large black dots depict the median of the group, and the vertical line spans the interquartile range. P-values were calculated using the Mann-Whitney-Wilcoxon test and the Benjamini-Hochberg method to correct for multiple hypothesis testing. Only significant P values (P < 0.05) are displayed. c, Correlation between the anti-S-RBD IgG levels and neutralizing antibody titers for every group (n = 420). The log transformation was performed by adding 1 to the value before taking the log2. The Spearman’s rank correlation coefficients (rs) and P values (P) are indicated.

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