Fig. 4: Pronounced mucosal inflammation after COVID-19 is not associated with LC. | Nature Immunology

Fig. 4: Pronounced mucosal inflammation after COVID-19 is not associated with LC.

From: Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

Fig. 4

a, Nasal cytokines measured by immunoassay in post-COVID participants (n = 64) compared with healthy SARS-CoV-2 naive controls (n = 25), and between the the cardioresp group (n = 29) and the recovered group (n = 31). The red values indicate significantly increased cytokine levels after FDR adjustment (P < 0.05) using two-tailed Wilcoxon signed-rank test. b, SARS-CoV-2 N antigen measured in sputum by electrochemiluminescence from recovered (n = 17) and pooled LC (n = 23) groups, compared with BALF from SARS-CoV-2 naive controls (n = 9). The horizontal dashed line indicates the lower limit of detection of the assay. c, Plasma S- and N-specific IgG responses measured by electrochemiluminescence in the LC (n = 35) and recovered (n = 19) groups. The median values were compared using two-sided Wilcoxon signed-rank tests, NS P > 0.05, *P < 0.05, **P < 0.01, ***P < 0.001 and ****P < 0.0001. The box plot center lines represent the median, the boundaries represent IQR and the whisker length represents 1.5× IQR.

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