Extended Data Fig. 3: Pretreatment single marker immunohistochemistry compared to posttreatment cell density and TLS density.

a, Line plots showing density of CD3, CD8, CD20, CD56 positive cells, and percent area of tissue positive for CXCL13 in pretreatment biopsy and post-neoadjuvant ICB HCC tumors. b, Dotplots showing correlation between post-treatment TLS density and pretreatment density of CD3, CD8, CD20, CD56 positive cells, and percent area of tissue positive for CXCL13 tissue. Statistical significance was determined by two-tailed t-test (a) and Pearson’s correlation (b).