Extended Data Fig. 5: Effect of Sstr2 deficiency on gut IEL subset representation in neonatal (P10), 3 weeks (weaning) and 8–10 weeks old (adult) mice.
From: An SSTR2–somatostatin chemotactic axis drives T cell progenitor homing to the intestines
Flow cytometry analysis of colon and small intestine IEL subset relative representation, shown as % of total T cells, comparing Sstr2+/− (or WT for P10) vs Sstr2−/− 8–10 weeks old mice (a, b), 3 weeks old (weaning) mice (c, d) and neonatal (P10) suckling pups (e, f). Data are shown as mean ± SEM and are representative of at least 3 independent experiments. DN = double negative, indicating CD4- CD8β-. Unpaired two-tailed T-test. *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001.
