Supplementary Figure 10: Relative selective advantages of gene pair versus single gene knockouts.
From: In vivo profiling of metastatic double knockouts through CRISPR–Cpf1 screens

Heat map of the change in log2 RPM abundance in lung metastases (n = 37 from ten mice) for each single gene knockout, relative to each modulatory second knockout. A positive value (red) means that the second knockout (rows) granted a relative selective advantage over the reference knockout (columns), whereas a negative value (blue) means the second knockout was relatively disadvantageous compared with the single knockout.