Supplementary Figure 13: Comparison of neuropil subtraction methods. | Nature Methods

Supplementary Figure 13: Comparison of neuropil subtraction methods.

From: Rapid mesoscale volumetric imaging of neural activity with synaptic resolution

Supplementary Figure 13

ΔF/F of calcium transients of the same 9,247 neurons in Fig. 3 calculated after neuropil subtraction using (a) CNMF-E method and (b) the standard method of using signal from neighboring pixels as neuropil contribution. (c) Pearson’s correlation coefficient distributions of the calcium traces for neurons in different cortical depths range. Also see Supplementary Video 10 for side-by-side comparison of example depths (D1 and D2).

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