Extended Data Fig. 10: Lineage similarities between in vivo and ex vivo datasets and fate maps for E11.5 progenitors. | Nature Methods

Extended Data Fig. 10: Lineage similarities between in vivo and ex vivo datasets and fate maps for E11.5 progenitors.

From: Comprehensive spatiotemporal mapping of single-cell lineages in developing mouse brain by CRISPR-based barcoding

Extended Data Fig. 10

a, PCA analysis of clonal cell-type compositions for in vivo and ex vivo clones. b, Pairwise lineage correlation (calculated as absolute Pearson correlation) of cell types captured both in vivo and ex vivo. The upper right shows the lineage relationship in vivo. The lower left shows the lineage relationship ex vivo. c, Examples of the fate of individual NPBM-restricted clones in Fig. 6f are shown on UMAP spaces of the E11.5 and OGN datasets. d, Fate maps for individual NPBL-restricted clones. An example of each fate is shown on the UMAP spaces of the E11.5 and OGN datasets.

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