Extended Data Fig. 6: Comparison of traditional Weiner-based 3DSIM algorithms including AO-3DSIM and 4BSIM.

a,The actin of α-TN4 lens epithelial cell, whose reconstruction is derived from AO-3DSIM. b, The membrane of sporulating B. subtilis, whose reconstruction is derived from 4BSIM. Scale bar: 2 μm. Scale on z-axis: a, 26 layers, 0.2μm per layer, b, 32 layers, 0.125μm per layer.