Extended Data Fig. 4: VM, striatal and cortical patterned organoids are enriched in corresponding brain region markers.
a-h, Volcano plots and corresponding relative gene expression heatmaps showing VM, striatal and cortical marker genes in differential expression analysis of cortical versus striatal and cortical versus VM organoids. Cortical organoids were enriched for cortical markers in comparison with striatal (a, e) and VM (d,h) tissues. b, f, Striatal organoids were enriched for striatal markers. c, g, VM organoids were enriched for mDA markers. p value was calculated using a Benjamin-Hochberg corrected Wald test using DESeq2.
